General info about the project

“Paediatric Brain Monitoring with Information Technology (KIdsBrainIT): Using IT Innovations to Improve Childhood Traumatic Brain Injury Intensive Care Management, Outcome, and Patient Safety“

Coordinator: University of Edinburgh, United Kingdom

P1 – University of Glasgow, United Kingdom
P2 – University Hospital Leuven, Belgia
P3 – Vall d’Hebron University Hospital, Spain
P4 – Universitatea de Medicină şi Farmacie „Grigore T. Popa” Iaşi (UMF)

Funding period: 01.06.2017-31.05.2019

Total amount UMF: 200.000 Euro (900.000 lei)



  • The project aims to test two clinically relevant hypotheses: After sustaining traumatic brain injury (TBI), paediatric patients with a longer period of measured cerebral perfusion pressure (CPP) maintained within the calculated optimal CPP (CPPopt) range have (1) an improved global clinical outcome, and (2) better tolerance against raised intracranial pressure (ICP).
  • To achieve this aim, we are developing a new multi-centre, multidisciplinary, and multinational Paediatric Brain Monitoring and Information Technology Group (KidsBrainIT), which includes a central data repository to store prospectively collected minute-resolution physiological, clinical, and outcome data. This infrastructure allows analyses on sub-sets of the data to apply novel data models and calculate validated indices as metrics of clinical management quality that are fed back to clinicians working within units contributing to KidsBrainIT. Developing this type of infrastructure is essential for investigations on how feedback of clinical management quality indices can influence and improve future treatment in later phases of KidsBrainIT. Data from the KidsBrainIT central data-bank are used to test our hypotheses.

Estimated results

  1. Improvement of paediatric TBI intensive care management in the UK, Europe, North America and beyond
  2. Validated results: ICP dose-response graphs for three clinically relevant agebands are readily translated back to clinical practice to allow a more refined evidence based management of raised ICP
  3. Journal and conference presentations
  4. Therapeutical guide.
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